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4 Previous studies in humans have demonstrated that activation of inflammation is an important part of the pathogenic process of CKD, and that macrophage infiltration and aggregation contribute to the accelerated progression of CKD

Some of the risks can be serious, such as fluid buildup in the lungs or a blood clot

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Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht von Graefes Archiv fr Klinische und Experimentelle Ophthalmologie

One possible explanation is that low serum vitamin B12 levels would trap folate as 5-methyltetrahydrofolate, prevent the generation of methionine from homocysteine, and therefore reduce protein synthesis and lean tissue deposition