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Mitochondrial dysfunction in central nervous system white matter disorders

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doi: 10.3389/fmicb.2018.02280 Received 01 June 2018 Accepted 06 September 2018 Published 04 October 2018 Volume 9 - 2018 Edited by Jack Wong, The Chinese University of Hong Kong, Hong Kong Reviewed by Maximino Manzanera, Universidad de Granada, Spain

Total GSH (tGSH) was calculated as the sum of reduced glutathione (GSH) and twice the amount of oxidized glutathione (GSSG)

The hypotheses on the pathogenesis of Alzheimers disease include cholinergic hypothesis, amyloid toxicity hypothesis, oxidative stress hypothesis, etc