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Cytokine 56 , 112115 (2011)

Dishes with ultralow attachment surface (Corning) were used for suspension and spheroid culture

In the cytosol/nucleus, SOD1, Prx1/2, GPx1/4 and the Grx/Trx1 systems, supported by abundant GSH, confine ROS and tune thiol switches on enzymes and transcriptional regulators while DNA repair machineries such as OGG1 and the base-excision repair (BER) pathway continuously survey and correct oxidative lesions, together establishing a compartment-aware redox homeostasis that enables signaling yet limits collateral damage (Le Gal et al

Among them are modulation of inflammation, promotion of angiogenesis, enhancement of matrix remodeling and activation of repair-linked transcription programs

(14) In fact, unlike plant-based proteins, which often contain lower cysteine levels, (15) whey provides this amino acid in a highly bioavailable form that the body can easily absorb and utilise