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Sirpiglenastat (DRP-104) induces antitumor efficacy through direct, broad antagonism of glutamine metabolism and stimulation of the innate and adaptive immune systems

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Metabolic alterations in medication-free patients with bipolar disorder: a 3T CSF-corrected magnetic resonance spectroscopic imaging study

for instance, oral doses up to 600 mg daily have been used for several weeks in pregnant women (such as those with gestational diabetes) without evident harm

This review deliberately excluded studies examining synthetic mitragynine analogs or chemically modified derivatives to maintain a mechanistic focus on naturally occurring kratom alkaloids as they occur in traditional and contemporary preparations [10]