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Signal Transduct Target Ther 6:94

Opioid analgesics, including acetaminophen and codeine phosphate tablets, and can prolong labor through actions which temporarily reduce the strength, duration, and frequency of uterine contractions

Furthermore, a subject of the present invention are pharmaceutical preparations (or pharmaceutical compositions) which comprise as active component a therapeutically effective dose of at least one compound of Formula I and/or a pharmaceutically acceptable salt thereof and a customary pharmaceutically acceptable carrier, i.e., one or more pharmaceutically acceptable carrier substances and/or additives

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It is often associated with pregnancy or hormonal medications