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Description

Several compounds target pathways that indirectly enhance antioxidant defenses by promoting GPX4 activity or GSH synthesis, thereby suppressing lipid peroxidation and inhibiting ferroptosis

Overall, barriers to clinical translation include nanoparticle pharmacokinetics, individual variability, and limited data on long-term safety

A.MaksoudR.BeerakaN

This review has established a practical framework for selecting device architectures and measurement strategies tailored to specific target biomarkers and their physiological contexts