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Lemmens G, Van Camp A, Kourula S, Vanuytsel T, Augustijns P (2021) Drug Disposition in the Lower Gastrointestinal Tract: Targeting and Monitoring

Once activated, EGFR interacts with SHC, leading to Tyr317 phosphorylation, which facilitates Grb2 binding and the formation of the SHC-Grb2-SOS complex, which is modulated by hydrogen peroxide

Liu PK: DNA damage and repair in the brain after cerebral ischemia

Histone methyltransferase SETDB1 inhibits TGF--induced epithelial-mesenchymal transition in pulmonary fibrosis by regulating SNAI1 expression and the ferroptosis signaling pathway

They are unquestionably ancient biological cofactors, and their simplicity and fundamental roles fit them as central to the emergence of life