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10:e2022EA002748

Intensive Care Med 2017

The antioxidant role of paraoxonase 1 and vitamin E in three autoimmune diseases

Genes with a Bonferroni-corrected P value of less than 0.05 were considered to be differentially expressed

In particular, we previously showed that CD38 is the main NAD + -hydrolyzing enzyme in mammalian tissues, and its upregulation largely accounts for age-dependent decline in NAD + 11,17,18,19