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Besides, NOX4 has been specifically linked to oncogenic H-Ras- (H-RasV12-) induced DNA damage and senescence, suggesting a potential role in HCV-related oncogenesis (111)

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While research has long focused on bacteria, the gut community also harbors viruses, archaea, fungi, protists, and, in some cases, multicellular eukaryotes such as helminths 2,3,4,5

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23 , R40R46 (2014)

These chemicals are generated from injured or stressed cells in response to ROS formation and operate as signaling factors to recruit and activate immune cells, sustaining inflammation (Albano et al., 2022)