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The Myth of B12 as a Performance Enhancer The Mayo Clinic weighs in definitively on this topic: Some researchers have studied vitamin B-12 to find out if it can raise energy and endurance during exercise

The reason why homocysteine is dangerous is because it damages cells and tissues of the arteries, triggers inflammatory reactions and enables cholesterol oxidation, which contributes to the build-up of atherosclerotic plaques the main culprits in cardiovascular disease (Kumar et al., 2017)

40 There is insufficient evidence to suggest that B12 on its own is beneficial in depression

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