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Activation of GPR109A by endogenous ligands such as -hydroxybutyrate (BHB) and butyrate, or by pharmacologic agents such as niacin, has been shown to exert anti-inflammatory, antioxidant, and barrier-protective effects

doi: 10.1038/nrm3699 192 CtesKBakala Ngoma JCDhouibRDouchetIMaurinDCarrireFet al