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Mast cells are essential for regulating inflammatory responses, which are considered vital during the early stages of wound healing

They are not intended to represent clinical evidence in humans, and AOD-9604 has not been approved by the FDA, EMA, or any other regulatory authority for any indication

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It raises questions for post-operative vascular surgery and disorders of venous return

For patients with CD, thiopurines can be added to glucocorticoids or budesonide to induce remission if the patient has had 2 exacerbations within a 12-month period or if tapering of glucocorticoids has failed[35]