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Acknowledgements This work is dedicated to the loving memory of Professor Nir Friedman zla dear friend, a mentor, and a source of inspiration

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LeMaistre Distinguished Chair in Thoracic Oncology, Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX Professor, Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX Research Interests An author of more than 260 peer-reviewed publications, Dr