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doi: 10.1159/000443995 76 JakszynPBinghamSPeraGAgudoALubenRWelchAet al

Rothstein JD

Summary and prospect With the discovery that FSP1 can regulate ferroptosis independent of GPX4, researchers have become more enthusiastic about finding GPX4-independent ferroptosis pathways

The aim of this paper is to review the role of ROS in normal physiological functions, ROS-mediated cellular signaling, and the role of oxidative stress in various chronic diseases and aging