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All potential benefits therefore must be weighed cautiously, and treatment is undertaken under medical supervision given that safety and efficacy are not yet established by regulatory authorities

P =0.001) and in tobacco-exposed MI compared to tobacco-nave MI rats (1271143 vs 84988

Xerosis conjunctivae precedes more serious damage

reduced L-glutathione has more direct measurement of blood GSH levels

Quantitative analysis revealed that infarct size reached approximately 65% in the Control group but was reduced to ~ 40% in hearts treated with 200 M GSNO, whereas 500 M GSNO did not confer significant cardioprotection (Fig