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As a result, there might be positive correlation between CSF UA levels and A42, which was thought to have a role in altered cognitive performance through the A42-related pathway (Maetzler et al., 2011)

Given the importance of BMP lipids for lysosomal function and the biochemical involvement of PG lipids in their biosynthesis, we postulate that these lipid changes indicate phagocytosis of cellular debris and lysosomal activity 15,16