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The major concerns: We dont have long-term safety data (20+ years) Youth uptake is a massive public health problem Many people end up dual-using (vaping AND smoking) Not FDA-approved for smoking cessation Variable quality and nicotine content between products Cost: $$ - Varies wildly depending on device and liquid Tier 3: Smoking Cessation Methods That Research Shows Probably Don't Work 11

Although studies are limited, there is some research to suggest a relationship between Vitamin B12 deficiency, fatigue, depression and foggy brain (Ref) Who is at risk for Vitamin B12 deficiency

In this mode, the nanoparticle initially affix itself to a specific transporter that is situated on the lateral aspect of the canal lumen ( 5 Targeting specific regions in the brain by nanoparticles Targeting specific regions of the brain for drug delivery has become increasingly important due to varying susceptibility of different brain areas in each neurological disease

Anticoagulants Anticoagulants target and disrupt clotting factors, slowing the bodys process of making clots

10.1002/j.2040-4603.2021.tb00173.x 218