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Phase I genes (CYP450 family) transform compounds into reactive intermediates

Flavonoids demonstrated sophisticated positive consequences for lymphoid and hematopoietic tissues than for solid tumors (4 patients with complete response (CR) and 21 with partial response (PR) among 525 patients in 12 trials), despite the relatively low rate of CR or partial response PR with any administration protocol (Table 2

[30] the inhibitory effect of selenium on the growth of microorganisms could be based on nonspecific incorporation of seleno-amino acids (SeMet, SeCys) instead of methionine and cysteine in proteins

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