SOD mimetic removes the products of ROMs that aids in the prevention of tissue damage and cellular energetic failure related with ischemia and perfusion (Salvemini and Cuzzocrea, 2002)
Consequently, the defense axis constituted by GPX4 and GSH is generally considered the core molecular apparatus for cellular resistance to ferroptosis, making it a focal point in OA pathogenesis research and targeted therapy exploration
These studies should focus on determining the optimal dose, enhancing bioavailability and evaluating the therapeutic effects of hesperidin in various human populations
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Islet is the site of dopamine synthesis [138,139,140]
