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Additionally, it was indicated that this prostaglandin may have an effect in two directions, namely activation of DP1 receptors, which reduces inflammation and preserves the barrier function of the skin [193], or activation of DP2 receptors, leading to the induction of chemotaxis in leukocytes and promoting the development of inflammation [194]

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While less than 20% of children under 10 years of age have cutaneous neurofibromas,14 they generally start appearing after puberty and increase in number as the patient grows older

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Combination therapy of Herceptin and Ad-mda7 inhibits growth of Her-2/neu overexpressing breast cancer in vivo