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Gut dysbiosis could persist for at least 6 months in COVID-19 patients after hospital discharge, and this chronic inflammatory condition may onset a wide range of neurological and neuropsychiatric symptoms in PASC patients 244

In the randomized controlled trial carried out by Glauser and colleagues, it was found that initial monotherapy with VPA for children with newly diagnosed childhood absence epilepsy exerted superior efficacy for seizure control without unsatisfactory adverse events compared to other AED such as lamotrigine [156]

The essential role of TAP gene products in presentation of antigenic peptides was demonstrated in mice with disrupted TAP genes

TAMs have been shown to play an important role in tumor cell genesis, development, and metastasis by regulating multiple signaling pathways

Given its role in neuronal survival and apoptosis, the MAPK pathway has become a key area of interest in SCA3 drug discovery