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Description

[Crossref] [PubMed] Abern MR, Larsen S, Levine LA

Ultrastruct Pathol

& Vermeulen, A

Abstract The androgen receptor (AR) signalling pathway has been intensively studied in the context of prostate cancer, where androgen deprivation therapy is part of the standard of care for metastatic disease

High-dose intravenous protocols (up to 50 mg/kg daily, ~3,500 mg for a 70 kg person) have been used safely in patients with metabolic disorders [8] , indicating a wide therapeutic margin