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Annals of Allergy, Asthma & Immunology, 127 (5), S117

doi: 10.1007/s00018-020-03574-z 53 MuthusamyT.CordesT.HandzlikM

The reviewed studies demonstrate the ability of the plant derivatives to modulate the inflammatory process by inhibiting pro-inflammatory and inducing anti-inflammatory cytokines, preventing edema formation and leukocyte migration to the focus of aggression (Vale et al., 2013)

Second, species-specific differences in enzyme activity limit the predictive value of conventional animal models

P53, a tumor suppressor, has been reported to inhibit cystine uptake and sensitize cells to ferroptosis by downregulating the expression of SLC7A11[88]