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3T3-L1 cells were cultured in 60 mm diameter dishes (8.4 104 cells/dish) and treated with NNMT inhibitor dissolved in culture media with/without adipogenic factors (1 mM IBMX, 1 M dexamethasone, 10 g/ml of insulin) during each of the scheduled media changes during the differentiation process (described above)

Because AOD9604 is studied in the context of selective fat metabolism modulation, adipocyte function regulation, and body composition effects, it is a subject in experiments related to metabolic health and weight regulationwithout implying outcomes outside of a research setting.