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doi: 10.18632/aging.103756 217 ZhaoL.YangW.ChenY.HuangF.LuL.LinC.et al

Cortisol has a wide range of effects on the body, including regulating metabolism, immune response, and blood pressure

doi: 10.1038/sj.ijo.0801740

Symptoms of DTs include: Fever Extreme agitation Seizures Extreme confusion Hallucinations High blood pressure Because alcohol withdrawal can be life-threatening, its crucial to detox under medical supervision

This blockage in autophagic flux ultimately leads to BAX/BAK oligomerization, activation of Caspase-3-mediated apoptosis, as verified in a POF model rat (Zhou et al., 2023)