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Curcumin mitigates neuronal degeneration by blocking the histone deacetylase 6 (HDAC6)-NLRP3 signaling pathway to suppress NLRP3 inflammasome-mediated inflammatory responses and counteracts -syn-induced neurotoxicity (Liu et al., 2011)

Spinal AT1R contributes to neuroinflammation and neuropathic pain via NOX2-dependent redox signaling in microglia

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and manual observations also confirmed that these were in multiple categories or pathways (Table 1), We used a cut off of log 2 fold =1.20