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Potential Side Effects, Safety Profile, and Regulatory Status of BPC 157 In preclinical studies, BPC 157 caused mild local irritation at the site of administration, which was the most commonly reported side effect but did not appear to lead to long-term issues

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Although several studies have stated that leptin can be an effective pharmaceutical tool for treating obesity in leptin-deficient states, the administration of exogenous leptin does not significantly decrease adiposity in the majority of instances of human obesity