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Gls-RNAi lines were sourced from the Tsinghua Fly Center (Beijing, China)

The presence of Akkermansia muciniphila , known to modulate BA metabolism, has also been associated with enhanced PD-1 blockade efficacy in MAFLD-related HCC, suggesting its potential as a predictive biomarker ( Beyond predicting treatment response, microbiota-BA axis alterations can serve as diagnostic and prognostic indicators

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