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Newly identified monogenic entities such as DADA2 (deficiency of adenosine deaminase 2) and VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome also exhibit vasculitic features and are associated with a high risk of thrombosis

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Due to their roles in inflammation, therapeutic agents targeting the MAPK and NF-B pathways offer significant advantages in treatment

Furthermore, while many multiplex assays are not strictly usable at the point of care (PoC), the small plastic cassettes that many of them use in analysis, facilitates the decentralization of testing and transport of patient samples

Gastroenterol Hepatol 2021, 44:112