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Since an intramolecular disulfide bond forms between the N- and C-terminal CRDs (Cys310-Cys629 and Cys303-Cys598), the higher amounts of reactive oxygen species cause Yap1 to undergo transitory redox-induced conformational changes that hide the NES

It was as if she was trying to scrub her brown skin off

This smooths out water fluctuations and gives a reliable trend line

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Building a routine that you can stick to every day is more valuable than a high-intensity "fix" that lasts only a week