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In addition, Ca 2+ signaling, chromatin changes, Wnt signaling, and RNA splicing also play an important role in the pathogenesis of these diseases

Output of BioFung is compared to representative organisms in the KEGG database (Supplementary Fig

The primary function of glutathione is to maintain the thiol groups of proteins in the reduced state

These findings indicate that MAPKAPK2 is required for melanocyte resistance to oxidative stress, but do not alone distinguish whether its protective role depends on protein abundance or kinase activity