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Description

Animals in the second group were treated with one intraperitoneal injection of polychlorinated biphenyl (Aroclor 1254) 500 mg kg -1 and were sacrificed after 7 days, while those in the third group were treated with intraperitoneal injection of 3-methylcholanthrene 20 mg -1 kg -1 day -1 for two days and were sacrificed 48 hours after treatment

Ascorbic acid, for example, effectively scavenges ROS and resynthesizes -tocopherol [48]

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The effect of forming glutamate from ketoglutarate is to deplete the mitochondrial pool of ketoglutarate, which is a key intermediate in the citric acid cycle