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Potential intermediate filament requirements in exophergenesis were an initial focus given that in humans, circulating IFs are clinical biomarkers of human neurodegenerative disease 36 , and IFs are major components of -synuclein-containing Lewy bodies that characterize Parkinsons disease neuropathology 37,38 , features that might intersect with extrusion biology and proteostasis balance

Fatigue and anxiety are under-recognized symptoms reported with AC and warrant further study

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You can also order B12 shots online through Defy Medicals convenient patient portal and administer the injections yourself

The 2 week evaluations at home with diaries were completed concomitantly by the patients (the first week of the month and the last week)