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Vivarelli S, Salemi R, Candido S, Falzone L, Santagati M, Stefani S, Torino F, Banna GL, Tonini G, Libra M

The authors also identified increased activities in 15 metabolic pathways and decreased activities in 45 metabolic pathways in AMD patients compared to that of the controls (Xue et al., 2023)

As a measure of mitophagy, mitolysosomes were quantified in sectioned retina immunolabeled with RBPMS for RGCs or vimentin for Mller glia

In sALS patients, deregulation of the cellular redox systems has been suggested by higher free radical levels found in the blood and serum of patients[32, 73], and evidence of oxidative damage includes the increase in protein carbonyls[34, 35, 74, 75], 8-OHdG[47, 49], MDA-modified proteins[34], 4-HNE protein conjugates[36, 76], and nitrotyrosine products[7779] in the spinal cord