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Ferroptosis, a distinct form of cell death driven by oxidative stress, has been implicated in the pathogenesis of various central nervous system disorders, including Parkinsons disease (Zhao et al., 2020), Alzheimers disease (Lane et al., 2021), Huntingtons disease (Skouta et al., 2014), epilepsy (Cai and Yang, 2021), and traumatic brain injury (Rui et al., 2021)

this association does not imply causation

However, they also noted that historic literature often suffers from methodological limitations, such as small sample sizes (averaging ~36 participants) and short study durations

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