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10.1002/mc.23092 137 VoT

Vitamin D in chronic kidney disease: a systemic role for selective vitamin D receptor activation

We found that MOTS-c treatment in NOD mice can reduce peri-insulitis in pancreatic islets, regulate cytokines such as interleukin-10 (IL-10) and IFN- in serum and isolated splenic T-cells, and prevent T-cell-driven disease transfer to NOD-SCID mice [14]