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An uncontrolled study of a self-limiting condition cannot establish efficacy, and this work was never replicated under controlled conditions which, four decades on, is itself the most informative fact about it

Additionally, copper ions in GHK-Cu can catalyze oxidation of certain peptides (such as those containing cysteine residues), leading to cross-reactivity and degradation

What exists in the peer-reviewed literature is a collection of case reports and small case series , and the majority of them describe harms rather than benefits

Do not self-administer unless instructed to do so by a medical professional