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Cinciripini PM, Tsoh JY, Wetter DW, et al

With the aim of delaying complications caused by poorly controlled hyperglycemia, health systems recommend early and personalized therapeutic intervention with hypoglycemic agents (World Health Organization, 2019), approximately 88% of the member countries of this organization use traditional and complementary medicine to maintain health and treat diseases such as T2D

Results showed that the combination of topical and oral glutathione significantly reduced melanin index and increased skin brightness compared to placebo and monotherapy groups

Keap1 is localized in neuronal and glial cytoplasmic inclusions in various neurodegenerative diseases

The redox-active iron form (Fe 2+ ) oxidizes lipids, in the Fenton reaction, which results in the production of a large amount of ROS, further oxidation of DNA and proteins are mediated by ROS, which results in insulin synthesis and secretion reduction, and ultimately apoptosis [45] (Fig