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The semaglutide component is the same molecule at the same doses, so the weight loss outcomes are expected to be comparable

Vitamin B12 Deficiency Has Nothing To Do With Weight Gain There is very little evidence to suggest that vitamin B12 affects the process of gaining or losing weight, despite the numerous techniques involved

Other drugs found to inhibit vitamin B 12 absorption from food include cholestyramine (a bile acid-binding resin used in the treatment of high cholesterol), chloramphenicol and neomycin (antibiotics), and colchicine (medicine for gout treatment)

In addition, a 2019 study published in JAMA Network Open suggests that post-menopausal women who habitually take high doses of vitamin B12, especially if they're also taking high doses of vitamin B6, are at higher risk of hip fracture