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[2] Supplements are commonly taken orally but may be administered via intramuscular injection to treat deficiencies

MECHANISM CATEGORIES SAFETY Side effects Generally well-tolerated in trials at the doses tested Injection-site reactions Known interactions Not characterized in Phase 3 Contraindications Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Not FDA-approved as a drug

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Generally, depression is becoming more common among adults in recent years