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10.3390/molecules28114491 12 BenjamimC

[55] experimentally demonstrated that both the organic extract and aqueous extract of Artemisia argyi exhibit significant hypoglycemic and anti-hyperglycemic effects in nicotinamide and streptozotocin-induced diabetic mouse models, whereas the volatile oil showed no such activity

Samples were diluted 1:2 with MES Buffer (0.2 M 2-(N-morpholino) ethanesulfonic acid/0.05 M phosphate/1 mM EDTA) and then assayed for total glutathione quantification by the addition of a mix containing: DTNB, glutathione reductase, NADP + , glucose-6-phosphate and glucose-6-phosphate dehydrogenase

The main mechanisms of this process are as follows: Through the FLT3-STAT5 signaling axis, the FLT3-ITD mutation directly increases phosphofructokinase platelet-type (PFKP), which in turn promotes glucose uptake, lactate generation, and glycolysis, all of which encourage the rapid proliferation of LSCs

Musial, C., Kuban-Jankowska, A., Gorska-Ponikowska, M