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Accumulation of reactive oxygen species after exposure to sublethal stress results in lethal damage to DNA, RNA, proteins, and lipids ( S also protects against oxidative stress ( Figure 3C ) (Landini et al., 2014)

10.1021/acs.chemrev.5b00597 30 KaiserS

10.1016/j.compbiomed.2022.105389 149 LiY.DouY.Da Veiga LeprevostF.GeffenY.CalinawanA

An ideal antioxidant must meet certain criteria to be effective including a fast absorption rate, chelating redox metallic compounds, work in cell membranes as well as in aqueous medium, and induce changes in gene expression to help cells mitigate ROS (Rahman, 2007

primary malignancy, OR 0.51 [0.27-0.94]), and with each additional Elixhauser comorbidity (OR 0.88 [0.85-0.92]) were less likely to undergo MI resection