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The studies on rat models revealed that AST accrues in animal tissues without any lethal effects [269, 270, 271]

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Reproduced with permission from Elsevier publisher (journal citation 158)

ii) nutrients and antibiotics could be prepared as a compound drug for clinical use, iii) nutrients and antibiotics could be chemically crosslinked and treated essentially as distinct pharmaceuticals for clinical use

The aerosol performance of the combined powder formulations was first evaluated using the next generation impactors (NGI) with Breezhaler at a flow rate of 90 L/min