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The Potential Molecular and Cellular Mechanism of Flavonoids for Iron Overload Based on the previous research results, we summarized the underlying mechanisms of flavonoids for treating iron overload according to the following three mechanisms: amelioration of iron status by various proteins and pathways, chelation of iron to reduce iron deposition, and resistance to oxidation to reduce iron overload-induced oxidative damage (Figure 3A)

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2009 Nov;18(11):29748