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The cystine/glutamate antiporter system Xc , a heterodimer composed of SLC7A11 and SLC3A2 on the cell membrane surface, takes up extracellular cystine in exchange for intracellular glutamate in a 1:1 ratio [9]

A reduction in -ketoglutarate, as reflected by lower -ketoglutarate/aconitate ratios, skews macrophages toward a proinflammatory phenotype

Nuytinck L, Narcisi P, Nicholls A, Renard JP, Pope FM, De Paepe A

Cysteines 1078 and 2991 cross-linking plays a critical role in redox regulation of cardiac ryanodine receptor (RyR)

Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility