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Status of hyperhomocysteinemia in China: results from the China Stroke High-risk Population Screening Program, 2018

Results showed that compound 22 ( 62 ), an oxazoline DNMTi, had potent inhibitory activity against DNMT1 (IC 50 = 150 M) (Figure 10) and also exhibited a dose-dependent anti-proliferative effect against HCT116 human colon carcinoma cells