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ifd-2() double mutant was suppressed to the same extent as in the single mutants, suggesting that ifd-1 and ifd-2 are likely to act in the same pathway to influence exopher production, and consistent with their colocalization in neurons (Fig

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Babies at birth are naturally exposed to the hyperoxic challenge due to the transition from the hypoxic intrauterine environment (pO 2 of 2025 mmHg) to extrauterine life (pO 2 of 100 mmHg)

PMID: 14745455