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Studies of SARS-CoV-2 have also shown that a specific region of the spike protein, known as the receptor binding domain, binds to a receptor called angiotensin-converting enzyme 2 (ACE2)

Its resource-impact materials also state that standard care for beta-thalassaemia still includes regular blood transfusions and iron chelation, and its appraisal documents note that pre-treatment or conditioning may affect fertility