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Pharmacologic activation of this pathway by metformin amplifies Treg populations (90, 104), while glycolysis inhibition with 2-deoxyglucose (2-DG) shifts metabolism toward FAO, thereby promoting a phenotypic switch from Th17 to Treg cells (82)

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[DOI] [PubMed] [Google Scholar] 171.Puspita L., Chung S.Y., Shim J.-W

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