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Meanwhile, the progressively deteriorating microenvironment characterized by fibrosis, vascular dysfunction, and inflammation accelerates the depletion of the primordial follicle pool via mechanisms such as aberrant activation followed by atresia or direct follicular degeneration, ultimately leading to diminished ovarian reserve 85,87

Ozone is a blue colored form of oxygen (its what makes the sky blue), and unlike regular oxygen, it is composed of three oxygen atoms (O3)

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doi: 10.3389/fpls.2026.1761092 Received 05 December 2025 Revised 23 January 2026 Accepted 16 February 2026 Published 12 March 2026 Volume 17 - 2026 Edited by Mizanur Rahman, The University of Texas Rio Grande Valley, United States Reviewed by Alfonso Ortega Garrido, Universidad de Extremadura, Spain Touhidur Rahman Anik, Texas Tech University, United States Updates Copyright 2026 Tian, Wang, Xing, Wu, Che, Zhang, Li, Chen and Sun